Understanding how the brain controls metabolism and reproduction in fruit flies.
Official title: Neural Substrates Controlling Metabolic and Reproductive State
Funded at University of Nevada Las Vegas · NIH-10888350 · Data updated 2026-11-12
This study is looking at how the brains of fruit flies help them manage their energy and reproduction based on their surroundings, which could help us understand similar processes in humans and improve our knowledge of metabolic disorders.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nevada Las Vegas NIH-funded |
| Lab location | 1 site (Las Vegas, United States) |
| Project start | July 14, 2023 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $187,678 |
| NIH project number | 5R16GM150433-02 |
| Project ID | NIH-10888350 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with metabolic disorders such as polycystic ovarian syndrome or adult-onset diabetes mellitus.
✕Less likely to help
Patients with metabolic conditions unrelated to nervous system regulation may not receive direct benefits from this research.
What this research studies
This research investigates the neural mechanisms that regulate metabolic and reproductive states in the fruit fly, Drosophila melanogaster. By utilizing the genetic and cellular tools available in these organisms, the study aims to identify how the brain responds to environmental changes to optimize energy use and reproduction. The findings could provide insights into the nervous system's role in metabolic disorders, which are often poorly understood in humans. The research will involve mapping the neural circuits involved in these processes, potentially revealing conserved biological principles applicable to more complex animals, including humans.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of metabolic disorders in humans, paving the way for new treatment strategies.
How similar studies have gone: While this research explores novel aspects of neural control over metabolism, similar studies in other organisms have shown promising results in understanding metabolic regulation.
Where this research is happening
-
University of Nevada Las Vegas
Las Vegas, United States Active
Researchers
- Principal investigator: Meiselman, Matthew Ramiah — University of Nevada Las Vegas
- Study coordinator: Meiselman, Matthew Ramiah
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.