Understanding how the brain controls memory retrieval.
Posterior cingulate cortex and executive control of episodic memory
This study is looking at how a specific part of the brain helps us remember things and make decisions, and it could help people with memory issues, like those with Alzheimer's disease, understand their condition better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11079538 on NIH RePORTER |
What this research studies
This research investigates the role of the posterior cingulate cortex (PCC) in managing how we retrieve and use memories. It aims to understand how this brain region interacts with other areas involved in memory and decision-making. By studying both human and non-human primate data, the research will explore how different parts of the PCC contribute to the regulation and integration of memories during decision-making processes. Patients may benefit from insights into how memory functions are affected in conditions like Alzheimer's disease.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research are individuals experiencing memory issues, particularly those diagnosed with Alzheimer's disease or related dementias.
Not a fit: Patients with memory issues not related to Alzheimer's disease or those with other neurological conditions may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for memory-related conditions such as Alzheimer's disease.
How similar studies have performed: Previous studies have shown promising results regarding the role of the PCC in memory processes, indicating that this research builds on established findings.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Foster, Brett — University of Pennsylvania
- Study coordinator: Foster, Brett
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.