NIH-funded research R21 grant

Understanding how the brain controls coordinated hand and jaw movements during eating.

Official title: Towards a neurobiology of "oromanual" motor control: behavioral analysis and neural mechanisms

Funded at Northwestern University at Chicago · NIH-10819032 · Data updated 2026-11-12

This study is looking at how our brain helps us move our jaw and hands together when we eat, using special tools to track these movements, and it aims to find ways to improve treatments for people with movement disorders.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionNorthwestern University at Chicago
NIH-funded
Lab location1 site (Chicago, United States)
Project startSeptember 1, 2023
Project endAugust 31, 2025
Funding year2023
Award (this year)$440,000
NIH project number1R21NS135642-01
Project IDNIH-10819032 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals experiencing difficulties with coordinated hand and jaw movements, such as those with neurological disorders affecting motor control.

Less likely to help

Patients with conditions unrelated to motor control or those who do not experience difficulties with hand and jaw coordination may not benefit from this research.

What this research studies

This research investigates the neurobiology behind coordinated movements of the jaw and hands, particularly during food-handling activities. By using advanced techniques like electromyography and machine learning, the study aims to capture and analyze the movements of both the jaw and hands simultaneously. This approach will help uncover the neural mechanisms that govern these complex behaviors, providing insights into how the brain coordinates these actions. Patients may benefit from a better understanding of motor control, which could lead to improved therapies for disorders affecting these functions.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of motor control, potentially leading to better treatments for conditions that impair hand and jaw coordination.

How similar studies have gone: While the specific approach of studying coordinated hand-jaw movements is relatively novel, similar research in motor control has shown promising results in understanding neural mechanisms.

Where this research is happening

  • Northwestern University at Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Shepherd, Gordon M — Northwestern University at Chicago
  • Study coordinator: Shepherd, Gordon M

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.