Understanding how the brain controls bladder function in older adults

Investigation of brain mechanisms involved in the Urinary Continence mechanism associated with aging

['FUNDING_R01'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-11076222

This study is looking at how the brain affects bladder control, especially for older adults who experience sudden urges to go to the bathroom, and it will use helpful techniques to understand which parts of the brain can make this issue better or worse, with the goal of finding better treatments for those who struggle with incontinence.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded)
Locations1 site (PITTSBURGH, UNITED STATES)
Trial IDNIH-11076222 on ClinicalTrials.gov

What this research studies

This research investigates the brain mechanisms that contribute to urinary incontinence, particularly urgency incontinence, in older adults. By using biofeedback techniques, the study aims to identify specific brain circuits involved in bladder control and how they may change with aging. The researchers will differentiate between brain mechanisms that exacerbate incontinence and those that may help manage it, ultimately seeking to improve treatment options for affected individuals. Patients may participate in behavioral therapy sessions to help explore these brain functions.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults aged 65 and above who experience urgency incontinence.

Not a fit: Patients under the age of 65 or those without urinary incontinence may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for urinary incontinence in older adults, improving their quality of life.

How similar studies have performed: Previous research has shown promising results using biofeedback to improve bladder control, indicating potential for success in this new investigation.

Where this research is happening

PITTSBURGH, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.