Understanding how the brain controls bladder fullness and urination
Bladder fullness signaling and the neural control of continence
This study is looking at how the brain helps control when we need to go to the bathroom, focusing on the signals it gets when the bladder is full, to find better ways to help older adults with bladder issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10819553 on NIH RePORTER |
What this research studies
This research investigates the neural circuits that control bladder function, particularly how the brain processes signals related to bladder fullness. It aims to identify specific neurons that detect and relay information about bladder distention, which is crucial for initiating urination. By studying the interactions between different brain regions involved in bladder control, the research seeks to fill knowledge gaps that could lead to improved treatments for lower urinary tract symptoms (LUTS), especially in the elderly. The approach involves examining the activity of neurons in the brain that are responsible for integrating bladder signals and coordinating the appropriate response.
Who could benefit from this research
Good fit: Ideal candidates for this research are elderly individuals experiencing lower urinary tract symptoms or bladder control issues.
Not a fit: Patients who do not have bladder control issues or are not elderly may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for individuals suffering from bladder control issues, particularly among the elderly.
How similar studies have performed: Previous research has shown promise in understanding neural control of bladder function, suggesting that this approach could yield valuable insights.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Verstegen, Anne ("Hanneke") — Beth Israel Deaconess Medical Center
- Study coordinator: Verstegen, Anne ("Hanneke")
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.