Understanding how the brain cancels balance signals during movement

Neural Computations Underlying Cancellation of the Vestibular Consequences of Voluntary Movement

['FUNDING_R01'] · JOHNS HOPKINS UNIVERSITY · NIH-11057967

This study looks at how a part of the brain called the cerebellum helps us keep our balance by figuring out the difference between what we expect to feel when we move and what we actually feel, and it aims to find ways to help older adults and others who have trouble with balance.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorJOHNS HOPKINS UNIVERSITY (nih funded)
Locations1 site (BALTIMORE, UNITED STATES)
Trial IDNIH-11057967 on ClinicalTrials.gov

What this research studies

This research investigates how the brain's cerebellum helps us manage balance by estimating and canceling out the signals from our inner ear that occur when we move. It aims to uncover the mechanisms that allow the brain to differentiate between expected and actual sensory input during active movements. By studying how these processes are learned and adapted, the research seeks to improve our understanding of balance and movement control, which is crucial for maintaining stability. The findings could lead to better strategies for managing balance-related issues, especially in aging populations.

Who could benefit from this research

Good fit: Ideal candidates for this research include older adults or individuals experiencing balance issues due to vestibular dysfunction.

Not a fit: Patients with stable balance and no history of vestibular disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance treatments for balance disorders, improving mobility and quality of life for patients.

How similar studies have performed: Previous research has shown promising results in understanding vestibular processing, indicating that this approach could yield valuable insights.

Where this research is happening

BALTIMORE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.