Understanding how the brain and immune system interact during food allergies
Official title: Project 2: Neuroimmune Interaction Mechanisms in Food Allergy
Funded at Food Allergy Science Initiative, INC. · NIH-11088826 · Data updated 2026-11-12
This study is looking at how our immune system and nervous system work together when we have food allergies, and it hopes to find new ways to help people manage their allergic reactions better.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Food Allergy Science Initiative, INC. NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project start | May 14, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $593,250 |
| NIH project number | 5P01AI179273-02 |
| Project ID | NIH-11088826 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with diagnosed food allergies, particularly those who experience severe allergic reactions.
✕Less likely to help
Patients without food allergies or those who do not experience significant allergic reactions may not benefit from this research.
What this research studies
This research investigates the complex interactions between the immune system and the nervous system in response to food allergens. By utilizing advanced techniques such as optogenetics and in vivo imaging, the study aims to identify the specific neural circuits activated during allergic reactions and how these circuits influence physiological and behavioral responses. Patients may benefit from insights into how their bodies react to allergens, potentially leading to new therapeutic approaches for managing food allergies.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve the management of food allergies and reduce the severity of allergic reactions.
How similar studies have gone: Previous research has shown promise in understanding neuroimmune interactions, suggesting that this approach could yield valuable insights into food allergy mechanisms.
Where this research is happening
-
Food Allergy Science Initiative, INC.
Cambridge, United States Active
Researchers
- Principal investigator: Liberles, Stephen Daniel — Food Allergy Science Initiative, INC.
- Study coordinator: Liberles, Stephen Daniel
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.