Understanding how the brain adapts to help people with aphasia recover language skills after a stroke

Functional reorganization of the language and domain-general multiple demand systems in aphasia

NIH-funded research Boston University (Charles River Campus) · NIH-10604322

This study is looking at how the brain helps people with aphasia, a language problem often caused by strokes, to recover their speaking skills, so that we can find better and more personalized ways to help them communicate again.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBoston University (Charles River Campus) NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10604322 on NIH RePORTER

What this research studies

This research investigates the brain mechanisms involved in language recovery for patients with aphasia, a condition that affects many stroke survivors. By examining how different brain regions interact during language processing, the study aims to identify effective and personalized treatment strategies. The researchers will analyze changes in brain activity and connectivity in both language-specific and general cognitive networks. This approach could lead to a better understanding of how the brain reorganizes itself to support language recovery.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who have experienced a stroke and are suffering from aphasia.

Not a fit: Patients who have not had a stroke or do not exhibit symptoms of aphasia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and tailored therapies for individuals recovering from aphasia after a stroke.

How similar studies have performed: Previous research has shown promise in understanding brain plasticity and recovery mechanisms in stroke patients, suggesting that this approach could yield valuable insights.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.