Understanding how the body's internal clock affects health and metabolism
Molecular mechanisms of mammalian circadian clock function
This study is looking at how our body's internal clock affects our health, especially how problems with this clock can lead to issues like obesity, diabetes, and cancer, and it aims to find new ways to help manage these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-11098391 on NIH RePORTER |
What this research studies
This research investigates the molecular mechanisms behind the mammalian circadian clock, which regulates the timing of various biological processes. By studying how disruptions to this clock can lead to health issues like obesity, diabetes, and cancer, the research aims to uncover the underlying genetic and biochemical pathways involved. The team will utilize advanced equipment to continuously measure gene expression and metabolic changes over time, providing insights into how circadian rhythms influence health. Patients may benefit from findings that could lead to new strategies for managing conditions linked to circadian disruption.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals experiencing circadian rhythm disruptions, such as shift workers or those with sleep disorders.
Not a fit: Patients with stable circadian rhythms and no related health issues may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and preventive measures for conditions like obesity, diabetes, and cardiovascular diseases.
How similar studies have performed: Previous research has shown promising results in understanding circadian rhythms and their impact on health, indicating that this approach has potential for significant advancements.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Green, Carla B. — Ut Southwestern Medical Center
- Study coordinator: Green, Carla B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.