Understanding how the body's internal clock affects health and metabolism
Molecular mechanisms of mammalian circadian clock function - Renewal - 1
This study looks at how our body's internal clock affects our health and can lead to problems like obesity and diabetes, helping people understand how their daily habits and surroundings might influence their well-being.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-10896929 on NIH RePORTER |
What this research studies
This research investigates the molecular mechanisms behind the mammalian circadian clock, which regulates the rhythmic expression of genes that influence various biological processes. By studying how disruptions to this clock can lead to health issues like obesity, diabetes, and cardiovascular diseases, the research aims to uncover the intricate feedback loops involving key proteins that control these rhythms. Patients may benefit from insights into how their daily routines and environmental factors impact their health and metabolic functions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing metabolic disorders such as obesity, diabetes, or cardiovascular diseases, particularly those affected by lifestyle factors like shift work or irregular sleep patterns.
Not a fit: Patients with stable metabolic conditions not influenced by circadian rhythms or those without any metabolic disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing and treating metabolic disorders linked to circadian disruptions.
How similar studies have performed: Previous research has shown promising results in understanding circadian rhythms and their impact on health, indicating that this approach has potential for significant advancements.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Green, Carla B. — Ut Southwestern Medical Center
- Study coordinator: Green, Carla B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.