Understanding How the Body Uses Nitrogen
Bioinorganic Chemistry of Nitrogen
['FUNDING_OTHER'] · CORNELL UNIVERSITY · NIH-11092177
This research explores how living things, including human systems and bacteria, manage important nitrogen compounds that affect processes like blood vessel regulation and cell energy.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CORNELL UNIVERSITY (nih funded) |
| Locations | 1 site (ITHACA, UNITED STATES) |
| Trial ID | NIH-11092177 on ClinicalTrials.gov |
What this research studies
Our bodies and other living organisms rely on special metal-containing proteins to handle nitrogen compounds, which are crucial for many biological functions. For example, nitric oxide helps control blood vessel widening in humans, while other nitrogen forms are used by bacteria, including those that can cause illness. This project aims to uncover the exact ways these proteins work, focusing on how they process different nitrogen molecules. We will identify new enzymes and study how they choose specific nitrogen compounds, which could help us understand both normal body functions and how pathogens operate.
Who could benefit from this research
Good fit: This foundational research does not directly involve patient participation at this stage, but future studies building on this knowledge could benefit individuals with cardiovascular issues or bacterial infections.
Not a fit: Patients seeking immediate treatment options or direct clinical intervention would not find direct benefit from this basic science project.
Why it matters
Potential benefit: Understanding these fundamental processes could lead to new ways to manage conditions related to blood vessel function or to combat infections caused by certain bacteria.
How similar studies have performed: While the specific mechanisms being explored are novel, the broader field of bioinorganic chemistry has a long history of successfully uncovering fundamental biological processes.
Where this research is happening
ITHACA, UNITED STATES
- CORNELL UNIVERSITY — ITHACA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LANCASTER, KYLE M — CORNELL UNIVERSITY
- Study coordinator: LANCASTER, KYLE M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.