Understanding how the body switches between breaking down and creating glucose
Elucidating the mechanism behind oscillation between glycolysis and gluconeogenesis
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-11077791
This study is looking at how our bodies control sugar levels, especially in people with adult-onset diabetes, to find new ways to help manage their glucose better and improve their overall health.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-11077791 on ClinicalTrials.gov |
What this research studies
This research investigates the mechanisms that control how our bodies manage glucose levels, particularly focusing on the processes of glycolysis and gluconeogenesis. By employing advanced techniques such as liquid chromatography-mass spectrometry and mathematical modeling, the researchers aim to quantify the rates and energies involved in these metabolic processes. This comprehensive approach seeks to provide a deeper understanding of metabolism, which could lead to innovative treatments for conditions like adult-onset diabetes. Patients may benefit from insights gained that could improve glucose regulation and overall metabolic health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with adult-onset diabetes who are seeking improved methods for glucose control.
Not a fit: Patients with type 1 diabetes or those without any metabolic disorders may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for better managing blood glucose levels in patients with diabetes.
How similar studies have performed: Previous research has shown promise in understanding metabolic processes, but this approach aims to provide a novel and more detailed perspective on glucose regulation.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PARK, JUNYOUNG O. — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: PARK, JUNYOUNG O.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: adult onset diabetes, Adult-Onset Diabetes Mellitus, Cancers