Understanding how the body stores fat during overeating
Testing the Adipose Expandability Hypothesis In Vivo During Overfeeding
This study is looking at how our bodies store extra fat when we eat too much and how that affects our health, especially for people with obesity or metabolic syndrome, to see if different amounts of fat cell growth can change how well our bodies handle insulin and overall health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lsu Pennington Biomedical Research Ctr NIH-funded |
| Lab location | 1 site (Baton Rouge, United States) |
| Project ID | NIH-11004614 on NIH RePORTER |
What this research studies
This research investigates how the body expands its fat storage capacity in response to excessive calorie intake. It focuses on the mechanisms of fat cell growth and the relationship between fat storage and metabolic health, particularly in individuals with obesity and metabolic syndrome. By using a randomized controlled trial, the study will assess how different levels of fat cell formation affect insulin sensitivity and overall health outcomes. Participants may undergo procedures to measure fat cell characteristics and their impact on metabolic conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults who are overweight or obese and may be experiencing metabolic health issues such as insulin resistance or type 2 diabetes.
Not a fit: Patients who are underweight or have no metabolic health concerns may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into obesity-related diseases and improve strategies for managing metabolic health.
How similar studies have performed: Previous studies have shown varying results regarding fat cell expansion and metabolic health, indicating that this area of research is still evolving and may provide novel insights.
Where this research is happening
Baton Rouge, United States
- Lsu Pennington Biomedical Research Ctr — Baton Rouge, United States (Active)
Researchers
- Principal investigator: White, Ursula — Lsu Pennington Biomedical Research Ctr
- Study coordinator: White, Ursula
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.