Understanding how the body senses internal signals in aging monkeys
Official title: Development of a lifespan monkey model of interoception
Funded at University of California at Davis · NIH-10742545 · Data updated 2026-11-12
This study looks at how monkeys' ability to feel their own heartbeats changes as they get older, which could help us understand more about emotions and health in both monkeys and people, and might lead to better treatments for age-related issues.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $433,950 |
| NIH project number | 1R21AG080198-01A1 |
| Project ID | NIH-10742545 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research are older adults experiencing cognitive decline or related health issues.
✕Less likely to help
Patients who are not elderly or do not have any interoception-related health concerns may not benefit from this research.
What this research studies
This research investigates how the ability to sense internal physiological signals, known as interoception, changes as monkeys age. By developing behavioral tasks to evaluate cardiac interoceptive ability in rhesus monkeys, the study aims to understand the neurobiological and environmental factors that influence this ability. The findings could help in creating treatments for age-related diseases and improve our understanding of cognitive processes related to emotions and health. The research will also explore how variations in heart function relate to interoceptive ability, providing insights that could be applicable to humans.
Why it matters
Potential benefit: If successful, this research could lead to new treatments and interventions for age-related diseases and improve overall health in older adults.
How similar studies have gone: While this approach is innovative, previous research has shown that understanding interoception can lead to significant advancements in treating related health conditions.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Bliss-Moreau, Eliza — University of California at Davis
- Study coordinator: Bliss-Moreau, Eliza
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.