Understanding how the body senses cold pain
Molecular and Computational Dissection of Cold Nociception
This study is looking at how our bodies sense cold pain and why it happens, which could help people who experience pain from cold temperatures find better treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgia State University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10981899 on NIH RePORTER |
What this research studies
This research investigates the cellular and molecular mechanisms that allow the body to detect cold pain, which is crucial for survival. It focuses on how specific ion channels in nerve cells respond to cold temperatures and how these responses can lead to pain sensations. By studying these processes, the research aims to uncover the interactions between cold detection and other sensory pathways, which could help explain conditions like neuropathic pain. Patients may benefit from insights that could lead to new treatments for pain related to cold sensitivity.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing cold allodynia or hyperalgesia, particularly those with conditions like neuropathic pain or multiple sclerosis.
Not a fit: Patients who do not experience cold sensitivity or pain related to temperature changes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients suffering from cold-related pain conditions.
How similar studies have performed: Previous research has shown promise in understanding sensory mechanisms related to pain, suggesting that this approach could yield valuable insights.
Where this research is happening
Atlanta, United States
- Georgia State University — Atlanta, United States (Active)
Researchers
- Principal investigator: Cox, Daniel N — Georgia State University
- Study coordinator: Cox, Daniel N
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.