Understanding how the body responds to SARS-CoV-2 infection.
Alveolus as Incubator: Functional Genomic Dissection of the Host Response to SARS-CoV-2 Infection.
['FUNDING_OTHER'] · WASHINGTON UNIVERSITY · NIH-10879777
This study is looking at how the body reacts to the COVID-19 virus, especially when the immune system goes into overdrive and causes problems, and it's aimed at finding ways to help patients feel better by understanding these reactions better.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-10879777 on ClinicalTrials.gov |
What this research studies
This research investigates the body's inflammatory response to SARS-CoV-2, the virus responsible for COVID-19. It focuses on a phenomenon known as Cytokine Storm Syndrome (CSS), where the immune system overreacts and causes harm to the body. By studying specific immune cells and the role of autophagy, the research aims to uncover how these processes can be manipulated to improve patient outcomes. The project employs innovative methods to explore the interactions between the virus and the host's immune response.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have been infected with SARS-CoV-2 and are experiencing severe inflammatory responses.
Not a fit: Patients who have not been infected with SARS-CoV-2 or those with mild symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that better manage the inflammatory response in COVID-19 patients.
How similar studies have performed: Other research has shown promising results in understanding immune responses to viral infections, suggesting that this approach could yield valuable insights.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ORVEDAHL, ANTHONY W — WASHINGTON UNIVERSITY
- Study coordinator: ORVEDAHL, ANTHONY W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.