Understanding how the body responds to Coccidioides infections
Molecular and cellular analysis of host response to Cocci
This study is looking at how your immune system reacts to Coccidioides infections, which can cause problems like pneumonia, and it's for anyone interested in understanding how different immune cells respond to this infection to help improve treatment options.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11004149 on NIH RePORTER |
What this research studies
This research investigates the body's immune response to Coccidioides infections, which can lead to various health issues, including pneumonia and central nervous system diseases. By utilizing advanced techniques like transcriptomics and single-cell RNA sequencing, the study aims to analyze how different immune cells react to the infection. Patient samples and in vitro models will be used to establish a detailed profile of the immune response, helping to identify variations that may influence disease outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Coccidioides infections, particularly those experiencing chronic symptoms or complications.
Not a fit: Patients who do not have a history of Coccidioides infections or related health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients affected by Coccidioides infections.
How similar studies have performed: Previous research has shown promise in understanding immune responses to infections, suggesting that this approach may yield valuable insights.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Sil, Anita — University of California, San Francisco
- Study coordinator: Sil, Anita
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.