Understanding how the body responds to a severe lung infection caused by a specific bacteria.
Official title: Multi-omics of murine respiratory melioidosis
Funded at University of Washington · NIH-10896453 · Data updated 2026-11-12
This study is looking at how our bodies fight off melioidosis, a serious infection caused by a specific bacteria, using both mouse experiments and patient samples to find better ways to treat it.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $194,375 |
| NIH project number | 5R21AI178273-02 |
| Project ID | NIH-10896453 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have been diagnosed with melioidosis or are at high risk for this infection.
✕Less likely to help
Patients with other types of infections or those not affected by Burkholderia pseudomallei may not benefit from this research.
What this research studies
This research investigates melioidosis, a serious infection caused by the bacteria Burkholderia pseudomallei, which can lead to pneumonia and high mortality rates. The team uses a mouse model to study the disease and has conducted extensive analyses on patient samples to identify how the body reacts to this infection. By combining insights from both animal models and human data, the research aims to uncover mechanisms of host defense and develop targeted therapies for better treatment outcomes.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and better survival rates for patients suffering from melioidosis.
How similar studies have gone: Previous research has shown promise in understanding similar infections through multi-omics approaches, indicating potential for success in this novel investigation.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: West, Timothy Eoin — University of Washington
- Study coordinator: West, Timothy Eoin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.