Understanding how the body regulates protein intake

Mechanism and Modulation of the homeostatic setpoint for protein feeding

NIH-funded research University of California, San Francisco · NIH-10891664

This study is looking at how our brains help us decide how much protein we need to eat, using fruit flies to learn more about the process, which could help us understand our own eating habits better.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-10891664 on NIH RePORTER

What this research studies

This research investigates the mechanisms behind how animals, including humans, regulate their need for protein consumption. By studying the neural circuits in fruit flies, the researchers aim to uncover how changes in physiological needs can alter the target level of protein intake. The study will utilize advanced techniques to manipulate these circuits and observe the resulting behaviors, providing insights into the homeostatic setpoint for protein feeding. This could lead to a better understanding of dietary needs and behaviors in humans.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 who are interested in understanding their dietary behaviors and protein consumption.

Not a fit: Patients who do not consume protein or have specific dietary restrictions that exclude protein may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved dietary recommendations and interventions for individuals struggling with protein intake.

How similar studies have performed: Previous research has shown success in using Drosophila as a model for studying dietary behaviors, indicating that this approach has potential for yielding valuable insights.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.