Understanding how the body recovers after surgery, focusing on pain and confusion.
Mechanisms involved in postoperative recovery: a focus on pain, delirium, and neuroinflammation
This study is exploring how our immune system affects how well people recover after surgery, especially regarding pain and confusion, and it's looking at how things like age and gender play a role, all to help make recovery easier for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Dallas NIH-funded |
| Lab location | 1 site (Richardson, United States) |
| Project ID | NIH-10922713 on NIH RePORTER |
What this research studies
This research investigates the biological mechanisms that affect how patients recover after surgery, particularly looking at pain and delirium. It focuses on the role of immune cells in the brain and blood that may influence recovery outcomes. By using advanced technologies and experimental models, the research aims to identify how factors like age and sex impact these immune responses and, consequently, recovery. The goal is to better predict and improve postoperative recovery experiences for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals undergoing surgical procedures, particularly older adults who may be at higher risk for complications like pain and delirium.
Not a fit: Patients who are not undergoing surgery or those with pre-existing severe cognitive impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing pain and delirium in postoperative patients, enhancing their recovery experience.
How similar studies have performed: Previous research has shown promising results in understanding the role of immune responses in postoperative recovery, suggesting that this approach could yield valuable insights.
Where this research is happening
Richardson, United States
- University of Texas Dallas — Richardson, United States (Active)
Researchers
- Principal investigator: Burton, Michael D — University of Texas Dallas
- Study coordinator: Burton, Michael D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.