Understanding how the body reacts to a mixed meal to predict metabolic health.

Metabolic Responses to an Oral Mixed Meal Tolerance Test: Intra-individual changes, correlates, and prognostic significance

NIH-funded research Boston University Medical Campus · NIH-10868602

This study is looking at how your body reacts to a meal to find early signs of heart and diabetes issues, so we can help you stay healthy before any problems arise.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBoston University Medical Campus NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10868602 on NIH RePORTER

What this research studies

This research investigates how individual metabolic responses to a mixed meal can reveal early signs of cardiometabolic diseases such as diabetes and cardiovascular issues. By conducting an oral mixed meal tolerance test, researchers will analyze changes in various metabolites in the blood before and after eating. This approach aims to identify subtle metabolic dysfunctions that may not be evident in a resting state, allowing for earlier intervention and management of health risks. The study will involve collecting and analyzing blood samples to create a comprehensive metabolic profile.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals at risk for cardiometabolic diseases, including those with obesity, diabetes, or cardiovascular conditions.

Not a fit: Patients who are already diagnosed with advanced cardiometabolic diseases may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved methods for early detection and prevention of cardiometabolic diseases.

How similar studies have performed: Previous research has shown that metabolic profiling can successfully identify risk factors for cardiometabolic diseases, indicating that this approach has potential for significant findings.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.