Understanding how the body protects itself from infections
Immunometabolic Mechanisms of Protection against Infection
['FUNDING_R21'] · NIMML INSTITUTE, INC. · NIH-11058208
This study is looking at how our body's immune system fights off infections, especially from a harmful germ called Clostridioides difficile, to find new ways to treat infections without using regular antibiotics, which could help patients get better faster.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NIMML INSTITUTE, INC. (nih funded) |
| Locations | 1 site (Blacksburg, UNITED STATES) |
| Trial ID | NIH-11058208 on ClinicalTrials.gov |
What this research studies
This research investigates the immunometabolic mechanisms that help the body defend against infections, particularly focusing on Clostridioides difficile, a harmful bacterium. The team at the NIMML Institute is exploring how these mechanisms can influence disease severity and treatment outcomes in both infectious and autoimmune diseases. By examining how bacterial toxins affect cells, the research aims to identify new therapeutic strategies that do not rely on traditional antibiotics. Patients may benefit from insights that could lead to more effective treatments for infections.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals suffering from Clostridioides difficile infections or those with autoimmune diseases.
Not a fit: Patients with infections not related to Clostridioides difficile or those who do not have autoimmune conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new, more effective treatments for infections that do not rely on antibiotics.
How similar studies have performed: Other research has shown promise in exploring immunometabolic pathways, suggesting potential for success in this novel approach.
Where this research is happening
Blacksburg, UNITED STATES
- NIMML INSTITUTE, INC. — Blacksburg, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HONTECILLAS, RAQUEL — NIMML INSTITUTE, INC.
- Study coordinator: HONTECILLAS, RAQUEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.