Understanding how the body fights tick-borne infections

Molecular basis of immunity to tick-borne rickettsioses

NIH-funded research State University New York Stony Brook · NIH-10899502

This study is looking at how our immune system fights off tick-borne diseases, like Rocky Mountain Spotted Fever, to help improve how we diagnose and treat these infections for people who get them.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionState University New York Stony Brook NIH-funded
Lab location1 site (Stony Brook, United States)
Project IDNIH-10899502 on NIH RePORTER

What this research studies

This research investigates the immune response to tick-borne diseases, which have been increasing in incidence across the United States. The team aims to identify the molecular mechanisms that enable the body to develop immunity against these infections, including Rocky Mountain Spotted Fever and others. By studying the immune responses in detail, the researchers hope to improve diagnosis and treatment options for patients affected by these diseases. The approach includes analyzing immune cells and their interactions with tick-borne pathogens to develop better preventive strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who have been diagnosed with tick-borne diseases or those who are at high risk of exposure to ticks.

Not a fit: Patients who do not have tick-borne diseases or are not at risk of exposure to ticks may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved vaccines and treatments for tick-borne diseases, enhancing patient outcomes.

How similar studies have performed: Previous research has shown promise in understanding immune responses to tick-borne diseases, but this specific approach is novel and aims to fill existing gaps in knowledge.

Where this research is happening

Stony Brook, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.