Understanding how the androgen receptor works in the body
Biochemical, structural and molecular dissection of androgen receptor transcriptional activity
This study is looking at a protein called the androgen receptor, which plays an important role in male development and is connected to health issues like prostate cancer and hair loss, to help find better treatments for these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Science Center NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project ID | NIH-11178853 on NIH RePORTER |
What this research studies
This research investigates the androgen receptor (AR), a key protein that influences male development and is linked to various health issues like prostate cancer and hair loss. The study uses advanced techniques such as electron microscopy and x-ray crystallography to explore how the AR is activated and inhibited at a molecular level. By examining the interactions between the AR and other proteins, the research aims to uncover the mechanisms that regulate AR activity, which could lead to better treatments for related disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with disorders related to androgen receptor dysfunction, such as metastatic prostate cancer or androgenetic alopecia.
Not a fit: Patients with conditions unrelated to androgen receptor activity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved therapies for conditions associated with abnormal androgen receptor activity.
How similar studies have performed: Previous research has shown promising results in understanding receptor mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
San Antonio, United States
- University of Texas Hlth Science Center — San Antonio, United States (Active)
Researchers
- Principal investigator: Wasmuth, Elizabeth Victorina — University of Texas Hlth Science Center
- Study coordinator: Wasmuth, Elizabeth Victorina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.