Understanding how the amygdala contributes to pain
Amygdala pain mechanisms
This study is looking at how a part of the brain called the amygdala affects chronic pain and aims to find new ways to help people manage their pain by understanding how different brain cells work together during this process.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas Tech University Health Scis Center NIH-funded |
| Lab location | 1 site (Lubbock, United States) |
| Project ID | NIH-11002283 on NIH RePORTER |
What this research studies
This research investigates the mechanisms of chronic pain, focusing on the role of the amygdala, a brain region involved in emotions. It aims to understand how neuroimmune signaling between different cell types in the brain contributes to the transition from acute to chronic pain. By examining how certain neurons and glial cells interact during pain, the study seeks to identify potential therapeutic targets to alleviate neuropathic pain. Patients may benefit from insights that could lead to new pain management strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing acute pain that may transition to chronic pain, particularly those with neuropathic pain conditions.
Not a fit: Patients with chronic pain not related to neuroimmune mechanisms or those with non-neuropathic pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for chronic pain that are more effective and targeted.
How similar studies have performed: Previous research has shown promising results in understanding the role of the amygdala in pain modulation, suggesting that this approach could yield significant insights.
Where this research is happening
Lubbock, United States
- Texas Tech University Health Scis Center — Lubbock, United States (Active)
Researchers
- Principal investigator: Neugebauer, Volker — Texas Tech University Health Scis Center
- Study coordinator: Neugebauer, Volker
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.