Understanding how temperature preferences affect sleep regulation in fruit flies
Official title: Molecular and Neural Mechanisms of Temperature Preference Rhythm in Drosophila
Funded at University of California at Davis · NIH-11004665 · Data updated 2026-11-12
This study is looking at how fruit flies manage their body temperature throughout the day and how this affects their sleep, hoping to find clues that could help us understand similar patterns in people.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | January 1, 2024 |
| Project end | December 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $362,250 |
| NIH project number | 5R35GM152154-02 |
| Project ID | NIH-11004665 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research would be individuals experiencing sleep disorders or disturbances related to circadian rhythm disruptions.
✕Less likely to help
Patients with sleep disorders not related to circadian rhythms or temperature regulation may not benefit from this research.
What this research studies
This research investigates the molecular and neural mechanisms that regulate body temperature rhythms (BTR) and their relationship to sleep regulation, using fruit flies (Drosophila) as a model organism. The study aims to uncover how these temperature preferences change throughout the day and how they relate to the circadian clock, which is crucial for maintaining overall health and homeostasis. By examining the genetic and environmental factors influencing these rhythms, the research seeks to provide insights that could be applicable to understanding similar processes in humans.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of sleep disorders and temperature regulation in humans, potentially informing new treatments.
How similar studies have gone: Previous research using Drosophila has successfully contributed to our understanding of circadian rhythms and their genetic underpinnings, suggesting a strong potential for this approach.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Hamada, Fumika — University of California at Davis
- Study coordinator: Hamada, Fumika
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.