Understanding how telomeres stay connected during cell division
Official title: Mechanisms of Telomere Cohesion
Funded at New York University School of Medicine · NIH-10927201 · Data updated 2026-11-12
This study is looking at how certain proteins help keep the protective ends of our chromosomes together when cells divide, which could help us understand more about aging and cancer, so patients can learn how this affects their health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 11, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $423,750 |
| NIH project number | 5R35GM149355-02 |
| Project ID | NIH-10927201 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing age-related conditions or those diagnosed with cancers associated with telomere dysfunction.
✕Less likely to help
Patients with conditions unrelated to telomere biology or those who are not experiencing aging-related issues may not benefit from this research.
What this research studies
This research investigates the mechanisms that keep telomeres, the protective ends of chromosomes, cohesive during cell division. By examining the role of specific proteins and processes involved in maintaining this cohesion, the study aims to uncover how these mechanisms contribute to cellular aging and cancer development. Patients may benefit from insights into how telomere cohesion affects the stability of their cells, particularly in the context of aging and malignancies. The research employs advanced molecular biology techniques to analyze telomere behavior in various cell types.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating age-related diseases and cancers by targeting telomere cohesion mechanisms.
How similar studies have gone: Previous research has shown promising results in understanding telomere dynamics, suggesting that this approach could yield valuable insights into cellular aging and cancer.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Smith, Susan — New York University School of Medicine
- Study coordinator: Smith, Susan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.