Understanding how telomere lengths vary in plants and their impact on evolution
Molecular mechanisms and evolution of natural telomeric variation
This study looks at how the length of protective chromosome caps in monkeyflowers affects their growth and survival, and it hopes to find clues that could help us understand aging and health issues in humans.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kansas Lawrence NIH-funded |
| Lab location | 1 site (Lawrence, United States) |
| Project ID | NIH-11137759 on NIH RePORTER |
What this research studies
This research investigates the variation in telomere lengths in the plant monkeyflower (Mimulus) and how this variation influences the fitness and evolution of the organism. Telomeres, which protect chromosome ends, can affect an organism's health and longevity, with implications for aging and related diseases. By studying these mechanisms in plants, the research aims to uncover insights that may be relevant to human health, particularly in understanding aging and disease predisposition.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would be individuals interested in the genetic factors influencing aging and related health conditions.
Not a fit: Patients with no interest in genetic research or those not affected by aging-related diseases may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide insights into the biological mechanisms behind aging and associated diseases in humans.
How similar studies have performed: While this research focuses on a novel plant system, similar studies in other organisms have shown promising results in understanding telomere biology and its implications for health.
Where this research is happening
Lawrence, United States
- University of Kansas Lawrence — Lawrence, United States (Active)
Researchers
- Principal investigator: Choi, Jae Young — University of Kansas Lawrence
- Study coordinator: Choi, Jae Young
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.