Understanding how TAZ affects the tumor environment in aggressive breast cancer

Who could benefit from this research

What this research studies

This research investigates the role of TAZ, a protein involved in cell signaling, in the tumor microenvironment of triple-negative breast cancer (TNBC). The study aims to understand how TAZ influences the behavior of immune cells and tumor progression, particularly in the context of TNBC, which is known for its aggressive nature and lack of targeted therapies. By using mouse models, researchers will explore how TAZ expression impacts the recruitment and function of immune suppressive cells that can affect tumor growth and response to treatment. This could lead to new insights into potential therapeutic strategies for patients with TNBC.

Why it matters

Where this research is happening

• University of Toledo Health Sci Campus
  Toledo, United States Active

Researchers

• Principal investigator: Zhang, Jianmin — University of Toledo Health Sci Campus
• Study coordinator: Zhang, Jianmin

Related research

Other NIH-funded projects on the same topics.

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.