Understanding how T cells recognize bacteria and viruses
Song - Proj 3
This study is looking at how your immune system's T cells recognize germs like bacteria and viruses, and it’s for anyone interested in understanding how their immune system works better by using new technology to analyze T cells more effectively.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project ID | NIH-10852732 on NIH RePORTER |
What this research studies
This research investigates the immune system's T cells, which recognize various antigens like bacteria and viruses through their unique receptors. By analyzing the T-cell receptor (TCR) repertoire, the study aims to uncover insights into an individual's immune history and potential. The researchers will develop advanced computational methods to process large datasets from sequencing technologies, allowing them to identify the binding specificity of TCRs more efficiently. This approach may help in associating TCRs with their specific targets, enhancing our understanding of immune responses.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a history of bacterial or viral infections who are willing to provide biological samples for analysis.
Not a fit: Patients who do not have a history of bacterial or viral infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for diagnosing and treating bacterial and viral infections.
How similar studies have performed: Previous research has shown promise in using sequencing data to analyze TCR repertoires, indicating that this approach may yield valuable insights.
Where this research is happening
Hanover, United States
- Dartmouth College — Hanover, United States (Active)
Researchers
- Principal investigator: Song, Li — Dartmouth College
- Study coordinator: Song, Li
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.