Understanding how synapses in the brain affect behavior
Bridging cellular and systems neuroscience: synaptic dynamics underlying behavior
This study is looking at how the way brain cells communicate affects the behavior of mice, especially when they learn new things, to help us understand how our brains adapt to learning and changes in our surroundings.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10922734 on NIH RePORTER |
What this research studies
This research investigates the relationship between synaptic transmission in the brain and behavior in mice. By examining how variations in synaptic strength correlate with changes in behavioral states and perceptual learning, the study aims to uncover the dynamic processes that govern neural communication. Using advanced techniques, researchers will monitor synaptic activity in the visual cortex of mice during different behavioral tasks. The goal is to bridge the gap between cellular mechanisms and overall brain function, providing insights into how the brain adapts to learning and environmental changes.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would be individuals interested in neurological conditions or cognitive enhancement.
Not a fit: Patients with conditions unrelated to synaptic function or those not experiencing cognitive or behavioral challenges may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing learning and adaptive behaviors in humans.
How similar studies have performed: Previous research has shown promising results in understanding synaptic dynamics and behavior, indicating that this approach has potential for significant breakthroughs.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Higley, Michael James — Yale University
- Study coordinator: Higley, Michael James
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.