Understanding how sympathetic nerves affect ovarian follicle development

The Role and Branching Dynamics of Sympathetic Nerves in Ovarian Folliculogenesis

NIH-funded research University of California, San Francisco · NIH-11030282

This study is looking at how certain nerves in the body affect the growth of ovarian follicles, which are important for female fertility, especially before puberty, to help us understand more about how these processes work and support ovarian health.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-11030282 on NIH RePORTER

What this research studies

This research investigates the role of sympathetic nerves in the development of ovarian follicles, which are crucial for female fertility. It aims to explore how these nerves influence the maturation of immature oocytes during the first wave of folliculogenesis, a process that occurs before puberty. By using advanced imaging techniques, the study will analyze the branching dynamics of sympathetic nerves and their signaling mechanisms. This could provide insights into the biological processes that govern fertility and ovarian health.

Who could benefit from this research

Good fit: Ideal candidates for this research are women aged 21 and older who are experiencing infertility or have concerns about ovarian health.

Not a fit: Patients who are not experiencing fertility issues or are outside the age range of 21 and older may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for addressing infertility in women.

How similar studies have performed: While the role of sympathetic nerves in reproductive health is an emerging area, similar studies have shown promising results in understanding nerve interactions in other biological processes.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.