Understanding how sympathetic nerves affect ovarian follicle development
Official title: The Role and Branching Dynamics of Sympathetic Nerves in Ovarian Folliculogenesis
Funded at University of California, San Francisco · NIH-11030282 · Data updated 2026-11-12
This study is looking at how certain nerves in the body affect the growth of ovarian follicles, which are important for female fertility, especially before puberty, to help us understand more about how these processes work and support ovarian health.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | March 1, 2023 |
| Project end | February 28, 2026 |
| Funding year | 2025 |
| Award (this year) | $44,923 |
| NIH project number | 5F31HD108875-03 |
| Project ID | NIH-11030282 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women aged 21 and older who are experiencing infertility or have concerns about ovarian health.
✕Less likely to help
Patients who are not experiencing fertility issues or are outside the age range of 21 and older may not benefit from this research.
What this research studies
This research investigates the role of sympathetic nerves in the development of ovarian follicles, which are crucial for female fertility. It aims to explore how these nerves influence the maturation of immature oocytes during the first wave of folliculogenesis, a process that occurs before puberty. By using advanced imaging techniques, the study will analyze the branching dynamics of sympathetic nerves and their signaling mechanisms. This could provide insights into the biological processes that govern fertility and ovarian health.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for addressing infertility in women.
How similar studies have gone: While the role of sympathetic nerves in reproductive health is an emerging area, similar studies have shown promising results in understanding nerve interactions in other biological processes.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Gaylord, Eliza Ann — University of California, San Francisco
- Study coordinator: Gaylord, Eliza Ann
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.