Understanding how sugars on blood cells affect their production
Official title: Project 2: Extracellular Glycosylation and Blood Cell Production
Funded at Versiti Wisconsin, INC. · NIH-11001980 · Data updated 2026-11-12
This study is looking at how sugars on blood cells and in their surroundings help control the production of blood cells, like platelets, to find ways to improve their formation and function for better health.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Versiti Wisconsin, INC. NIH-funded |
| Lab location | 1 site (Milwaukee, United States) |
| Project start | January 1, 2021 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $548,902 |
| NIH project number | 5P01HL151333-05 |
| Project ID | NIH-11001980 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with blood disorders or conditions affecting blood cell production.
✕Less likely to help
Patients with stable blood cell counts and no underlying blood disorders may not benefit from this research.
What this research studies
This research investigates the role of sugars on the surface of blood cells and in their surrounding environment in regulating blood cell production. It focuses on how these sugars interact with signals that guide the development and function of blood cells, including platelets and other blood components. By studying specific enzymes involved in sugar modification, the research aims to uncover mechanisms that could improve blood cell formation and function, which is crucial for maintaining health.
Why it matters
Potential benefit: If successful, this research could lead to new therapies for blood disorders by enhancing blood cell production and function.
How similar studies have gone: Other research has shown promising results in understanding the role of glycosylation in blood cell development, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Versiti Wisconsin, INC.
Milwaukee, United States Active
Researchers
- Principal investigator: Lau, Joseph Ty — Versiti Wisconsin, INC.
- Study coordinator: Lau, Joseph Ty
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.