Understanding how substance cues affect cravings in people recovering from addiction

Cue Incubation in Substance Use Disorders: Validation and Assessment of Mechanisms

NIH-funded research Univ of Maryland, College Park · NIH-10397679

This study is looking at how seeing or thinking about things related to drugs or alcohol can affect cravings and the chance of relapse for people recovering from addiction, and it aims to find ways to help those who might struggle during their recovery.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniv of Maryland, College Park NIH-funded
Lab location1 site (College Park, United States)
Project IDNIH-10397679 on NIH RePORTER

What this research studies

This research investigates how exposure to cues associated with substance use, such as alcohol or cocaine, can influence cravings and the risk of relapse in individuals recovering from addiction. By studying inpatients at a drug rehabilitation center, the research will measure changes in craving levels, brain activity, and biological markers related to cue reactivity. The goal is to identify mechanisms that contribute to increased cravings during the early stages of abstinence, which could help in developing targeted interventions for those at risk of relapse.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals currently undergoing treatment for cocaine use disorder in a residential rehabilitation setting.

Not a fit: Patients who are not currently in treatment for substance use disorders or those with other substance use issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing relapse in individuals recovering from substance use disorders.

How similar studies have performed: Previous studies have shown that cue reactivity is a significant factor in relapse for various substances, indicating that this approach has been successful in similar contexts.

Where this research is happening

College Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.