Understanding how structural variations in genes evolve
Learning about the evolution of structural variations from genomic and transcriptomic data
['FUNDING_OTHER'] · FLORIDA ATLANTIC UNIVERSITY · NIH-10850583
This study looks at how changes in our genes, like when genes get duplicated, can affect evolution and lead to diseases, and it's for anyone curious about how these genetic changes impact our bodies and health over time.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | FLORIDA ATLANTIC UNIVERSITY (nih funded) |
| Locations | 1 site (BOCA RATON, UNITED STATES) |
| Trial ID | NIH-10850583 on ClinicalTrials.gov |
What this research studies
This research investigates how structural variations in genes, such as gene duplications, contribute to evolutionary changes and human diseases. By analyzing genomic and transcriptomic data, the team uses computational methods to classify the evolutionary outcomes of these variations. The research focuses on understanding how gene duplications affect gene expression across different tissues and species, particularly in organisms like Drosophila and mammals. This approach aims to uncover the role of natural selection in shaping these genetic changes over time.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with genetic disorders or diseases linked to structural variations in their DNA.
Not a fit: Patients without any known genetic disorders or those not affected by structural variations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding of genetic factors in diseases and inform new therapeutic strategies.
How similar studies have performed: Previous research has shown success in understanding gene duplications and their evolutionary impacts, indicating that this approach is grounded in established scientific methods.
Where this research is happening
BOCA RATON, UNITED STATES
- FLORIDA ATLANTIC UNIVERSITY — BOCA RATON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ASSIS, RAQUEL — FLORIDA ATLANTIC UNIVERSITY
- Study coordinator: ASSIS, RAQUEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers