Understanding how strokes affect cognitive outcomes and recovery

DISCOVERY: Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY

NIH-funded research Massachusetts General Hospital · NIH-10929381

This study is looking at how strokes can affect thinking and memory after the event, especially for people who already have conditions like Alzheimer's, and it aims to find ways to help those at risk recover better.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10929381 on NIH RePORTER

What this research studies

This research investigates the relationship between stroke events and post-stroke cognitive impairment and dementia (PSCID), particularly focusing on how pre-existing brain conditions like Alzheimer's disease may influence recovery. By examining various demographic and clinical factors, the study aims to identify which types of strokes are more likely to lead to cognitive issues and how these can be prevented. The research involves a collaborative network of clinical sites that will assess acute stroke patients to gather comprehensive data on their outcomes. This information will help develop personalized treatment plans and improve future clinical trials.

Who could benefit from this research

Good fit: Ideal candidates for this research include adults over 21 who have experienced a stroke and may be at risk for cognitive impairment.

Not a fit: Patients who have not experienced a stroke or do not have any risk factors for post-stroke cognitive impairment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better prevention strategies and treatments for cognitive impairment following strokes.

How similar studies have performed: Previous research has shown promising results in understanding the cognitive impacts of strokes, but this study aims to explore new dimensions of this relationship.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injuryAlzheimer's disease and related dementiaAlzheimer's disease and related disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.