Understanding how stress granules respond to viral infections
Official title: Stress granules in virus infections
Funded at University of Toledo · NIH-10578897 · Data updated 2026-11-12
This study is looking at how tiny structures in our cells, called stress granules, help our bodies fight off viruses when we're stressed, and it aims to find out how these granules work and how they might lead to new treatments.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Toledo NIH-funded |
| Lab location | 1 site (Toledo, United States) |
| Project start | January 1, 2023 |
| Project end | December 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $490,086 |
| NIH project number | 1R15AI169398-01A1 |
| Project ID | NIH-10578897 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with viral infections or those at risk of such infections.
✕Less likely to help
Patients with non-viral infections or those not experiencing any form of viral illness may not benefit from this research.
What this research studies
This research investigates the role of stress granules, which are cellular structures that form in response to stress, particularly during viral infections. It aims to understand how these stress granules, specifically antiviral stress granules, help the body mount an effective defense against viruses. The study will explore the composition and dynamics of these granules and how they interact with viral components and the immune response. By examining these processes, the research seeks to uncover critical insights into host-virus interactions and potential therapeutic targets.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing antiviral responses in patients.
How similar studies have gone: Previous research has shown that understanding stress granules in the context of viral infections can lead to significant advancements in antiviral therapies.
Where this research is happening
-
University of Toledo
Toledo, United States Active
Researchers
- Principal investigator: Krishnamurthy, Malathi — University of Toledo
- Study coordinator: Krishnamurthy, Malathi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.