Understanding how stress and resilience affect aging and Alzheimer's disease

Who could benefit from this research

What this research studies

This research investigates the relationship between stress, resilience, and the development of Alzheimer's disease (AD) in older adults. By analyzing data from large population studies, the research aims to identify factors that may help protect against the harmful effects of stress on cognitive health. The study focuses on understanding how these factors interact with the biological changes associated with AD, particularly amyloid plaques and neurofibrillary tangles. This knowledge could inform future prevention strategies for AD.

Why it matters

Where this research is happening

• Massachusetts General Hospital
  Boston, United States Active

Researchers

• Principal investigator: Vannini, Patrizia — Massachusetts General Hospital
• Study coordinator: Vannini, Patrizia

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.