Understanding how stress affects thinking and decision-making
Cortical mechanisms of stress-induced cognitive impairment
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA-IRVINE · NIH-10833474
This study is looking at how stress affects our thinking and decision-making by checking how different parts of the brain work together when we're under stress, and it's for anyone interested in understanding how stress can impact our everyday choices.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA-IRVINE (nih funded) |
| Locations | 1 site (IRVINE, UNITED STATES) |
| Trial ID | NIH-10833474 on ClinicalTrials.gov |
What this research studies
This research investigates the impact of stress on cognitive functions, particularly focusing on how stress disrupts the connectivity of brain areas involved in decision-making. By examining the posterior parietal cortex, the study aims to uncover the mechanisms behind stress-induced cognitive impairment. The researchers will use a combination of physical, visual, and auditory stressors to observe changes in synaptic connections in the brain. This approach will help clarify how chronic stress affects the brain's ability to integrate sensory information and make decisions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing chronic stress or cognitive impairments related to stress.
Not a fit: Patients who do not experience stress-related cognitive issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving cognitive function in individuals affected by stress.
How similar studies have performed: Previous studies have shown that understanding the neural mechanisms of stress can lead to significant advancements in mental health treatments.
Where this research is happening
IRVINE, UNITED STATES
- UNIVERSITY OF CALIFORNIA-IRVINE — IRVINE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LUR, GYORGY — UNIVERSITY OF CALIFORNIA-IRVINE
- Study coordinator: LUR, GYORGY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.