NIH-funded research Fellowship grant

Understanding how stress affects the risk of suicidal thoughts

Official title: Stress experiences as markers of person-level vulnerability and temporal risk for near-term suicidal ideation

Funded at University of Notre Dame · NIH-10947074 · Data updated 2026-11-12

This study is looking at how stress and personal challenges can affect thoughts about suicide, and it’s for anyone who wants to help improve ways to prevent these thoughts by sharing their real-life experiences with stress.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of Notre Dame
NIH-funded
Lab location1 site (Notre Dame, United States)
Project startSeptember 28, 2023
Project endJune 30, 2026
Funding year2024
Award (this year)$48,974
NIH project number5F31MH135693-02
Project IDNIH-10947074 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals aged 21 and younger who have experienced significant stress and may be at risk for suicidal thoughts.

Less likely to help

Patients who do not experience stress or have no history of suicidal ideation may not benefit from this research.

What this research studies

This research investigates the relationship between stress experiences and the risk of suicidal ideation, focusing on how individual vulnerabilities and environmental factors interact. By examining both trait-like and state impulsivity, as well as emotion dysregulation, the study aims to identify specific conditions that may predict imminent suicidal thoughts. Participants will provide real-time data on their stress levels and experiences, allowing researchers to better understand the dynamics of stress and suicidal ideation. The goal is to enhance precision in suicide prevention interventions tailored to individual needs.

Why it matters

Potential benefit: If successful, this research could lead to more effective suicide prevention strategies tailored to individual stress experiences and vulnerabilities.

How similar studies have gone: Previous research has shown that understanding individual stress responses can improve suicide prevention efforts, indicating potential success for this approach.

Where this research is happening

  • University of Notre Dame
    Notre Dame, United States
    Active

Researchers

  • Principal investigator: Knorr, Anne — University of Notre Dame
  • Study coordinator: Knorr, Anne

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.