Understanding how stress affects reproductive aging in women

Center for Stress and Neural Regulation of Reproductive Aging Health Outcomes

NIH-funded research Brigham and Women's Hospital · NIH-11092953

This study is looking at how stress and hormone changes affect the health of older women, especially with symptoms like hot flashes and sleep problems, to help improve their well-being during and after menopause.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11092953 on NIH RePORTER

What this research studies

This research investigates the impact of stress and hormonal changes on the health of older women, particularly focusing on issues like hot flashes, sleep disturbances, cognitive changes, and increased risks for heart disease and dementia. The study aims to explore how stress responses and brain activity relate to these symptoms, using advanced brain imaging and other scientific methods. By examining these connections, the research seeks to improve women's health outcomes during and after menopause.

Who could benefit from this research

Good fit: Ideal candidates for this research are older women experiencing menopausal symptoms, particularly those with significant stress exposure.

Not a fit: Patients who are not experiencing menopausal symptoms or are younger than the typical menopausal age may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better management strategies for menopausal symptoms and associated health risks in older women.

How similar studies have performed: Other research has shown promising results in understanding the relationship between stress and reproductive health, indicating that this approach has potential for significant insights.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.