Understanding how stress affects reproductive aging in women
Center for Stress and Neural Regulation of Reproductive Aging Health Outcomes
['FUNDING_OTHER'] · BRIGHAM AND WOMEN'S HOSPITAL · NIH-10870121
This study is looking at how stress and hormonal changes affect the health of older women, especially regarding hot flashes, sleep problems, memory changes, and heart disease risks, to help understand how stress throughout life impacts these issues.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BRIGHAM AND WOMEN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10870121 on ClinicalTrials.gov |
What this research studies
This research investigates the impact of stress and hormonal changes on the health of older women, particularly focusing on issues like hot flashes, sleep disturbances, cognitive changes, and increased risks for heart disease and dementia. The study aims to explore how stress exposure throughout life influences these health outcomes and seeks to identify biological markers related to these changes. By utilizing advanced brain imaging and clinical assessments, the research will provide insights into the neural mechanisms involved in reproductive aging and its associated health risks.
Who could benefit from this research
Good fit: Ideal candidates for this research are perimenopausal and postmenopausal women experiencing vasomotor symptoms and related health issues.
Not a fit: Patients who are not experiencing menopausal symptoms or are not within the age range of perimenopause to postmenopause may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved management strategies for menopausal symptoms and better overall health outcomes for older women.
How similar studies have performed: Previous research has shown promising results in understanding the relationship between stress and reproductive health, indicating that this approach could yield valuable insights.
Where this research is happening
BOSTON, UNITED STATES
- BRIGHAM AND WOMEN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JOFFE, HADINE — BRIGHAM AND WOMEN'S HOSPITAL
- Study coordinator: JOFFE, HADINE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.