Understanding how stress affects bladder function differently in boys and girls.
Official title: Bladder Voiding After Stress Defeat Stress: Impact of Sex and Gonadal Hormones
Funded at Children's Hosp of Philadelphia · NIH-11075827 · Data updated 2026-11-12
This study looks at how stress affects how kids use the bathroom, especially comparing boys and girls, to understand why some children have trouble with bladder control when they're stressed, and it hopes to find better ways to help them.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | May 1, 2024 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $133,500 |
| NIH project number | 5R03DK139286-02 |
| Project ID | NIH-11075827 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include school-aged children experiencing lower urinary tract symptoms, particularly those affected by stress or anxiety.
✕Less likely to help
Patients who do not have lower urinary tract symptoms or are not affected by stress may not benefit from this research.
What this research studies
This research investigates how stress impacts bladder function in children, focusing on differences between boys and girls. It examines the role of gonadal hormones and how chronic social stress can lead to voiding issues, which are common in school-aged children. By using animal models, the study aims to uncover the biological mechanisms behind these differences and the influence of stress on bladder control. The findings could help identify better treatment strategies for children experiencing bladder problems related to stress.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for children suffering from bladder issues related to stress.
How similar studies have gone: Previous research has shown that stress can affect bladder function, but this study aims to explore sex-specific responses, making it a novel approach.
Where this research is happening
-
Children's Hosp of Philadelphia
Philadelphia, United States Active
Researchers
- Principal investigator: Van Batavia, Jason Philip — Children's Hosp of Philadelphia
- Study coordinator: Van Batavia, Jason Philip
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.