Understanding how stress affects alcohol's mood-boosting effects in social drinkers

Examining the Impact of Stress on the Emotionally Reinforcing Properties of Alcohol in Heavy Social Drinkers: A Multimodal Investigation Integrating Laboratory and Ambulatory Methods

['FUNDING_R01'] · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · NIH-11121851

This project explores how stress makes alcohol feel more rewarding for people who drink heavily in social settings.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN (nih funded)
Locations1 site (CHAMPAIGN, UNITED STATES)
Trial IDNIH-11121851 on ClinicalTrials.gov

What this research studies

This work aims to understand why alcohol seems to improve mood when people are stressed, especially in social situations. Researchers know that many people drink to relieve stress, and those who find alcohol very stress-relieving are more likely to develop alcohol use disorder. This project will look at how social stress, like being in new social settings, influences how rewarding alcohol feels. By using advanced methods like brain imaging, the goal is to better understand the social factors that drive heavy drinking.

Who could benefit from this research

Good fit: Ideal candidates for this type of research would be heavy social drinkers who experience stress and are interested in understanding the relationship between stress, social settings, and alcohol consumption.

Not a fit: Patients who do not consume alcohol or do not experience stress-related drinking may not directly benefit from this specific line of inquiry.

Why it matters

Potential benefit: If successful, this work could lead to new ways to prevent and treat alcohol use disorder by addressing the link between stress and alcohol's rewarding effects.

How similar studies have performed: While previous attempts to capture alcohol's stress-relieving effects experimentally have been inconsistent, this project builds on prior work indicating enhanced alcohol reward in novel social contexts.

Where this research is happening

CHAMPAIGN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.