Understanding how stress affects aging and diseases in women
MAE-WEST SCORE Career Enhance Core
['FUNDING_OTHER'] · CEDARS-SINAI MEDICAL CENTER · NIH-10903835
This study looks at how long-term stress affects aging and the risk of diseases like Alzheimer's, especially focusing on the differences between men and women, to help find ways to improve health as we get older.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CEDARS-SINAI MEDICAL CENTER (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-10903835 on ClinicalTrials.gov |
What this research studies
This research investigates the impact of chronic stress on aging and the development of diseases, particularly focusing on how these effects differ between men and women. It aims to uncover the biological mechanisms that contribute to the higher prevalence of Alzheimer's disease and related dementias in women as they age. By studying inflammatory mediators and their role in multi-organ dysfunction, the research seeks to identify potential interventions that could mitigate these age-related health issues. Patients may benefit from insights into how stress and gender influence their health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are older women who may be experiencing stress-related health issues or are at risk for Alzheimer's disease and related dementias.
Not a fit: Patients who are younger or do not have any risk factors for Alzheimer's disease or related dementias may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to targeted interventions that reduce the risk of Alzheimer's disease and related dementias in women.
How similar studies have performed: Other research has shown success in understanding sex differences in aging and disease, but this specific approach focusing on stress and inflammatory mediators is relatively novel.
Where this research is happening
LOS ANGELES, UNITED STATES
- CEDARS-SINAI MEDICAL CENTER — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BAIREY MERZ, CATHLEEN NOEL — CEDARS-SINAI MEDICAL CENTER
- Study coordinator: BAIREY MERZ, CATHLEEN NOEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer's disease and related dementia, Alzheimer's disease and related disorders, Alzheimer's disease or a related dementia, Alzheimer's disease or a related disorder, Alzheimer's disease or related dementia