Understanding how stem cells maintain and repair organs
Organ-scale regulation of stem cell dynamics
['FUNDING_OTHER'] · STANFORD UNIVERSITY · NIH-11073018
This study looks at how adult stem cells in the Drosophila midgut, which can help repair and renew organs, respond to different signals in their surroundings, and it aims to help us understand how these processes work in human organs to keep them healthy.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-11073018 on ClinicalTrials.gov |
What this research studies
This research investigates the behavior of adult stem cells, which are crucial for the renewal and repair of organs. By using advanced imaging techniques and genetic tools, the study aims to uncover how these cells respond to various signals in their environment to maintain organ function. The research focuses on the dynamics of stem cells in the adult Drosophila midgut, which serves as a model for understanding similar processes in human organs. The goal is to build a framework that explains how individual cells contribute to the overall health and stability of tissues.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who may benefit from advancements in stem cell therapies.
Not a fit: Patients with conditions unrelated to stem cell dynamics or organ repair may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing organ repair and regeneration in humans.
How similar studies have performed: Other research has shown promising results in understanding stem cell behavior, making this approach both relevant and potentially impactful.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: O'BRIEN, LUCY ERIN — STANFORD UNIVERSITY
- Study coordinator: O'BRIEN, LUCY ERIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.