Understanding how stem cells are controlled
Deciphering enhancer regulation in stem cells
['FUNDING_OTHER'] · CASE WESTERN RESERVE UNIVERSITY · NIH-11132935
This project aims to understand how special cells called stem cells grow and change, which is important for understanding diseases like cancer.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CASE WESTERN RESERVE UNIVERSITY (nih funded) |
| Locations | 1 site (CLEVELAND, UNITED STATES) |
| Trial ID | NIH-11132935 on ClinicalTrials.gov |
What this research studies
Our bodies have special cells called stem cells that can renew themselves and turn into many different cell types. This project looks at how certain genetic switches, called enhancers, control these stem cells. We want to understand how these switches work and how they are affected by other factors in the cell. Learning more about these processes could help us understand how diseases develop and how to potentially treat them.
Who could benefit from this research
Good fit: This foundational research is not directly recruiting patients but aims to benefit those affected by cancers and other developmental disorders in the long term.
Not a fit: Patients seeking immediate treatment options or direct clinical intervention would not find direct benefit from this basic science project.
Why it matters
Potential benefit: If successful, this work could lead to new insights into how diseases like cancer develop and how to guide stem cells for future therapies.
How similar studies have performed: This project builds on previous discoveries about how genetic switches work in stem cells, exploring new and untested mechanisms.
Where this research is happening
CLEVELAND, UNITED STATES
- CASE WESTERN RESERVE UNIVERSITY — CLEVELAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CAO, KAIXIANG — CASE WESTERN RESERVE UNIVERSITY
- Study coordinator: CAO, KAIXIANG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers, Disease, Disorder