Understanding how Staphylococcus bacteria attach to the skin
Mechanisms of staphylococcal skin colonization
This study is looking at how certain bacteria, called Staphylococcus, stick to our skin, which can help us understand how to better treat infections caused by harmful strains while also appreciating the good ones that protect us.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Medical Center NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project ID | NIH-11047552 on NIH RePORTER |
What this research studies
This research investigates the mechanisms by which Staphylococcus species adhere to the skin surface. While some Staphylococcus strains can cause disease, many are harmless and can even provide benefits by preventing harmful bacteria from colonizing the skin. The study focuses on a specific protein called Aap, which is believed to play a crucial role in this adherence process. By exploring how these bacteria interact with skin cells, the research aims to uncover new insights that could lead to innovative treatments for staphylococcal infections.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with skin conditions or those at risk of staphylococcal infections.
Not a fit: Patients who do not have any skin-related issues or are not at risk for staphylococcal infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance skin health and prevent infections caused by harmful bacteria.
How similar studies have performed: Previous research has shown promise in understanding bacterial interactions with the skin, suggesting that this approach could yield valuable insights.
Where this research is happening
Omaha, United States
- University of Nebraska Medical Center — Omaha, United States (Active)
Researchers
- Principal investigator: Fey, Paul D — University of Nebraska Medical Center
- Study coordinator: Fey, Paul D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.