Understanding how split-belt treadmill training can improve walking in people with Multiple Sclerosis

Neural Underpinnings and Sensory Feedback Augmentation During Split-belt Treadmill Training in People with Multiple Sclerosis

['FUNDING_FELLOWSHIP'] · COLORADO STATE UNIVERSITY · NIH-11065218

This study is looking at how walking on a special treadmill that makes each leg move at different speeds can help people with Multiple Sclerosis improve their walking, and it also tests if adding gentle electrical stimulation can make these improvements even better.

Quick facts

Phase['FUNDING_FELLOWSHIP']
Study typeNih_funding
SexAll
SponsorCOLORADO STATE UNIVERSITY (nih funded)
Locations1 site (FORT COLLINS, UNITED STATES)
Trial IDNIH-11065218 on ClinicalTrials.gov

What this research studies

This research investigates how split-belt treadmill training, where each leg moves at different speeds, can help improve walking difficulties in individuals with Multiple Sclerosis (MS). The study aims to explore the neural mechanisms that contribute to gait improvements and assess whether adding sensory feedback through techniques like transcutaneous electrical nerve stimulation (TENS) can enhance these benefits. Participants will engage in treadmill training while researchers monitor brain activity to understand how their bodies adapt to this unique training method.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults diagnosed with Multiple Sclerosis who experience gait difficulties.

Not a fit: Patients with stable gait and no significant walking difficulties may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved walking abilities and reduced fall risk for individuals with Multiple Sclerosis.

How similar studies have performed: Previous research has shown that split-belt treadmill training can improve gait in various populations, suggesting a promising avenue for enhancing mobility in individuals with MS.

Where this research is happening

FORT COLLINS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.