Understanding how spinal cord injuries affect nerve recovery.
Propriospinal Plasticity and Recovery After Incomplete Spinal Cord Injury.
This study is looking at how certain nerve cells in the spinal cord change after an injury and how those changes can affect recovery, with the goal of finding better ways to help people heal from spinal cord injuries.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Louisville NIH-funded |
| Lab location | 1 site (Louisville, United States) |
| Project ID | NIH-11223778 on NIH RePORTER |
What this research studies
This research investigates how certain neurons in the spinal cord change after an injury and how these changes can either help or hinder recovery. By using advanced techniques to trace and silence specific spinal cord neurons in animal models, the study aims to link anatomical changes to functional outcomes. The researchers will analyze the anatomy of these neurons before and after different types of spinal cord injuries, using innovative imaging methods and locomotor analysis to assess recovery. This approach could provide insights into improving rehabilitation strategies for individuals with spinal cord injuries.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 21 and older who have experienced an incomplete spinal cord injury.
Not a fit: Patients with complete spinal cord injuries or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance recovery after spinal cord injuries.
How similar studies have performed: Previous research has shown promise in understanding spinal cord plasticity, but this specific approach is relatively novel.
Where this research is happening
Louisville, United States
- University of Louisville — Louisville, United States (Active)
Researchers
- Principal investigator: Magnuson, David Sk — University of Louisville
- Study coordinator: Magnuson, David Sk
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.